At Ribocure, we are driven by science and innovation, with a mission to establish a world-leading company in RNA research and development, ultimately making a positive impact on patients worldwide.
The Role: Clinical Bioanalytical Scientist
Our clinical portfolio is growing, with our key siRNA assets advancing to later stages of clinical development, and with innovative approaches, such as extra-hepatic siRNA assets, advancing toward clinical phases. We are now looking for a Clinical Bioanalytical Scientist/Expert to support our Clinical Programs and our Clinical Sample Management Team with bioanalytical expertise throughout our clinical development programs.
This role will be part of the Clinical Pharmacology, Statistics & DMPK function. You will collaborate closely with others across our organization, in a dynamic and pragmatic, fast-paced biotech setting. You will work alongside colleagues in Clinical Operations, primarily the Sample Management Lead (SML), who oversees all aspects of sample management in our clinical trials and act as the primary contact with CROs involved in bioanalysis, method development and validation and oversees operational aspects of these deliverables. The successful candidate for this role, will provide expert technical oversight and scientific support for clinical bioanalytical activities, to facilitate internal decision making and regulatory compliance.
Priority will be given to candidates living in proximity to our Göteborg office in the vibrant GoCo area, to allow the majority of the work to be conducted on site. However, for the right candidate, we may also consider partly remote solutions, although with significant time spent at the Göteborg office on a regular basis.
Key Responsibilities
This role will collaborate closely with the Sample Management Lead (SML), the Clinical Pharmacology Lead, the Medical Director and other members of the clinical project teams, as well as with preclinical bioanalytical experts. You will be responsible for ensuring the scientific quality and technical feasibility of clinical bioanalytical activities. The successfull candidate will provide technical expertise in transfer of preclinical methods to the clinical setting, selection of bioanalytical CRO, developing appropriate clinical analytical assays, method development, validation, sample analysis and documentation, fulfilling regulatory expectations, across our clinical portfolio. A strong background in PK and ADA sample analysis is required. The ideal candidate would also have experience of supporting the analysis of PD biomarkers including method identification, development, validation, sample analysis and documentation to regulatory standards.
The successful candidate would not be required to conduct wet-work, however a strong background of hands-on laboratory experience in bioanalytical methodologies relevant to clinical siRNAs and/or other oligonucleotide ‑based therapeutics is key for being successful in this role.
An important part of the role is supporting the SML with expert input in contacts with clinical bioanalytical vendors, such as evaluation of CRO bioanalytical technical capabilities, communication and troubleshooting with CROs during method development, validation and sample analysis, work closely with the CRO on developing an integrated immunogenicity analysis strategy (including screening, confirmatory and Nab assay) and review and approval of analysis plans and reports. Ideally, and depending on the experience of the candidate, the succesfull candidate will also support the clinical teams with bioanalytical related regulatory interactions. Some operational support in sample management handling together with the SML, is also expected, in line with our “biotech hands-on, can-do” culture.
Close collaboration with the preclinical bioanalytical and translational teams, based at Suzhou Ribo Life Science Co., Ltd. in China, will be key for ensuring efficient transfer of preclinical bioanalytical expertise to the clinical setting.
Required Skills and Experience:
- Solid (eg 5+ years) previous hands-on experience in oligonucleotide relevant bioanalytical methodologies (including but not limited to LC-MS) relevant to clinical plasma and urine PK
- Solid previous hands-on experience of conducting ADA assessments, including developing multi-tiered integrated immunogenicity analysis strategies
- Adequate experience of working with bioanalysis of oligonucleotides in biological matrices, and if not yet an expert in the siRNA bioanalysis field – a strong interest and strong potential for becoming an expert in a reasonable time frame
- Solid, previous hands-on experience in successfully contributing to identification, development and validation of clinical PK and ADA methodologies in relation to clinical trials
- Solid, previous hands-on experience in documentation fulfilling regulatory standards in relation to clinical bioanalysis, such as:
o Technical review and approval of PK and ADA method development and validation protocols
o Review and approval of PK and ADA method validation (and potential cross-validation) reports
o Review of sample analysis data and bioanalytical reports
- Adequate understanding of pharmacokinetics and immunogenicity assessments in a clinical setting
- Solid experience and strong understanding of the clinical drug development process in a pharma industry or biotech setting, and how to ensure that bioanalytical activities are aligned with clinical development plans, clinical trial objectives and strategies
- Track-record in successful efficient cross-functional collaboration in a pharma industry or biotech setting, as well as with external partners, including with bioanalytical vendors in an international setting
- Strong written and verbal English. Strong communication skills and experience in working across different geographies and cultures
- Working style that thrives in an innovative, fast-paced entrepreneurial setting, with willingness to take on responsibility and demonstrating both strong collaboration skills, and the capacity for independent, self‑directed work
Desirable Skills and Experience:
- Experience in clinical bioanalysis of additional analytes, eg PD biomarkers
- Adequate understanding of how PKPD and Model Informed Drug Development can inform Clinical development programs
- Experience in regulatory interactions across the clinical development program, including late phase (Ph2b, Ph3 and submissions)
- Experience with biobanking, including sample collection, long‑term storage, and compliance with ethical and regulatory requirements across multiple countries, including country‑specific informed consent practices.
We offer more than a job – we offer a mission. You’ll be part of a tight-knit, friendly team working on real challenges with real potential. Your ideas matter. Your work matters. And your growth matters to us.
We encourage you to submit your CV and cover letter promptly, as applications will be reviewed on an ongoing basis. Final application deadline: June 21, 2026
Hiring manager: Lotta (Ann-Charlotte) Egnell , Global Head of Clinical Pharmacology, Statistics and DMPK
